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Mortality and Morbidity of Infectious Diseases
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Nearly all of the 13.7 million children and adults who die each year from an infectious disease live in developing countries.1, 2 In these countries, infectious diseases also disable millions of adults, diminishing their quality of life, decreasing productivity, and creating financial hardships for families.1-4
Infectious diseases include:
Worldwide, lower respiratory infections, HIV/AIDS, diarrheal diseases, and tuberculosis are among the top 10 causes of death; these disease along with malaria account for the top 10 causes of death in the developing world. Some diseases are curable, others are manageable with treatment, and many are preventable with vaccines and other tools. However, getting these interventions to the people in need to prevent or control disease has proven challenging.
| Mortality and Morbidity Due to Selected Infectious Diseases1, 2, 4-8 |
| Causes of Death |
Annual Deaths |
Annual DALYs* |
| Lower Respiratory Infections |
4.1 million |
94.5 million |
| Diarrheal Diseases |
2.1 million |
72.7 million |
| HIV/AIDS |
2 million |
58.5 million |
| Tuberculosis |
1.4 million |
34.2 million |
| Malaria |
889,185 |
33.9 million |
| Measles |
423,710 |
14.8 million |
| Neglected Diseases |
195,098 |
19 million |
| Sexually Transmitted Infections |
128,472 |
10.4 million |
| Polio |
1,195 |
34,399 |
| Other Infectious Diseases |
1.3 million |
28.5 million |
| Emerging Infectious Diseases |
N/A |
N/A |
*DALY = Disability-Adjusted Life Years, the years of healthy life lost due to disability, sickness
or premature mortality
N/A = not available |
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| 1 |
World Health Organization. WHO global burden of disease (GBD) 2002 estimates (revised). Available from: http://www.who.int/healthinfo/bodestimates/en/ |
| 2 |
Breman J, Alilio M, Mills A. 2004. Conquering the intolerable burden of malaria: what's new, what's needed: a summary. American Journal of Tropical Medicine & Hygiene 71:1-15. |
| 3 |
World Health Organization. Tuberculosis fact sheet no. 104. (accessed October 17, 2007), Available from: http://www.who.int/mediacentre/factsheets/fs104/en/ |
| 4 |
UNAIDS, World Health Organization 2007. AIDS epidemic update. Available from: http://data.unaids.org/pub/EPISlides/2007/2007_epiupdate_en.pdf |
| 5 |
Hotez PJ MD, Fenwick A et al. 2007. Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria. PLoS Medicine 3(No 5 e102). |
| 6 |
World Health Organization. 2007. Measles. Fact sheet no 286. Available from: http://www.who.int/mediacentre/factsheets/fs286/en/print.html |
| 7 |
Mathers CD, Lopez A, Stein C, Fat DM, Rao C, Inoue M, et al. 2005. Deaths and disease burden by cause: global burden of disease estimates for 2001 by World Bank country groups. Disease Control Priorities Project Working Paper No 18. Available from: http://www.dcp2.org/file/33/wp18.pdf |
| 8 |
World Health Organization. 2008. Global tuberculosis control: surveillance, planning, financing. Available from: http://www.who.int/tb/publications/global_report/2008/pdf/fullreport.pdf |
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